Best cbd oil for anxiety: Does it actually work?

If you’re looking for the best CBD oil for anxiety, we’ve found a product that seems to be popular with people experiencing anxiety.

Anxiety can come in many forms. The Mayo Clinic describes some examples of anxiety disorders “…include generalized anxiety disorder, social anxiety disorder (social phobia), specific phobias and separation anxiety disorder. You can have more than one anxiety disorder. Sometimes anxiety results from a medical condition that needs treatment.”

Remember it’s important to speak with your medical professional about adding CBD to your health regime. Anxiety can be caused by underlying health conditions like heart disease or diabetes.

The best CBD Oil for Anxiety: How does CBD help anxiety?

As far back as 1993 researchers have been looking at CBD to treat anxiety. A study was done by A. W. Zuardi, R. A. Cosme, F. G. Graeff and F. S. Guimarães, Effects of ipsapirone and cannabidiol on human experimental anxiety which found in human subjects “The results suggest that ipsapirone and CBD have anxiolytic (anti-anxiety) properties in human volunteers submitted to a stressful situation.”

Then in 2011 more research was conducted that found “Relative to placebo, CBD was associated with significantly decreased subjective anxiety”. This study titled Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report  looked at the underlying brain mechanisms to try and understand how CBD works to help with anxiety.

We’re still discovering how CBD works, but the answer to how it helps with anxiety may lie in the Endocannabinoid System or the ECS.

Introducing the Endocannabinoid System

Every mammal on planet Earth has an Endocannabinoid System or ECS. The ECS is a biological system that includes endocannabinoids which are cannabinoids that our bodies produce naturally.

Cannabidiol or CBD interacts with these ECS receptors located throughout the body. The ECS system is known to regulate a number of physiological and cognitive processes in the body including:

  • appetite
  • stress response
  • pain-sensation
  • mood
  • memory
  • contributing to exercise-induced euphoria
  • modulating locomotor activity

It’s not hard to imagine that a system that impacts so many critical body functions should be kept in “balance”.  This balance is often referred to as homeostasis. Many people believe that generalized social anxiety disorder or SAD is related to the ECS being out of balance.

CBD may help to bring the ECS into homeostasis and help to regulate these stress response and mood processes.

The best CBD Oil for Anxiety: What we have found

Looking for the best CBD oil for anxiety, we followed our general approach to selecting a reputable CBD company. You can read more about the Three things you need to know before buying CBD here.

In selecting the Best CBD Oil for Anxiety we’ve found that a Full Spectrum CBD Oil is most likely to show benefits. This is probably due to the “entourage effect” from whole plant CBD that is not processed to the point where it only contains CBD.

Receptra Naturals makes a product called Receptra Plus that seems to be perfect for those wanting to try CBD for anxiety.  Here’s what we like about this product:

  • Made from organically grown hemp in Colorado
  • Full Spectrum or Whole Plant formula
  • Concentration at 40 milligrams of CBD per dropper
  • Competitive price point

If you would like to try this product yourself, you can find the latest pricing here 

Pro Tip: If you would like to try CBD for a lower price, just select the Receptra Prime product that comes in a half ounce size and is priced at only $39.95 (at the time of this writing).  It’s half the strength of the Plus product, but it’s a good choice to see if it works for you.

The Risks of taking CBD Oil for Anxiety

CBD is considered to be non-toxic even in large amounts. A study in 2011 found CBD to be initially safe.

“Several studies suggest that CBD is non-toxic in non-transformed cells and does not induce changes on food intake, does not induce catalepsy, does not affect physiological parameters (heart rate, blood pressure and body temperature), does not affect gastrointestinal transit and does not alter psychomotor or psychological functions. Also, chronic use and high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans. Conversely, some studies reported that this cannabinoid can induce some side effects, including inhibition of hepatic drug metabolism, alterations of in vitro cell viability, decreased fertilization capacity, and decreased activities of p-glycoprotein and other drug transporters. Based on recent advances in cannabinoid administration in humans, controlled CBD may be safe in humans and animals. However, further studies are needed to clarify these reported in vitro and in vivo side effects.”


While continuing research into CBD and the role it might play in helping people with anxiety is needed, the current CBD products on the market might be worth trying.

One thought on “Best cbd oil for anxiety: Does it actually work?

  1. Thank you so much for this information. My husband has recently been suffering from social anxiety and after showing him this article he is ready to try CBD.

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